The Institute for Imaging Science and Computational Modeling (ICM) is part of the Charité University Hospital in Berlin, Germany. Our team of engineers and clinicians focuses on computational modeling of cardiovascular disease. The goal is to use both established and novel design and modeling techniques to study hemodynamic pathologies of various cardiovascular diseases such as valvular insufficiencies or aortic stenoses. Much of this research is aimed at developing and validating modeling tools to support the clinical decision-making process. This includes not only new approaches for non-invasive quantification of clinical parameters, but also methods to predict hemodynamic outcomes of interventions such as stenting or valve replacement.

Our team is investigating the feasibility of computational fluid dynamics (CFD) to accurately predict aortic hemodynamics before and after treatment. Over the years, we have developed a comprehensive and efficient workflow to perform accurate patient-specific CFD simulations based on medical imaging data. Combined with our large clinical database, our interdisciplinary work forms the basis of the ArtiCardio project, providing patient-specific anatomical and hemodynamic data covering a wide variability of pathological situations and, together with the flow solution, providing data to train the machine learning framework.